Endocrine Abstracts

Introduction: Coronavirus infection COVID19 spread by Sars-Cov-2 virus were announced by WHO as a pandemics in the end of 2019. As shown in many studies virus affects whole body, particularly endocrine system. There were information about thyroid disturbances after COVID19 infection. Fergana valley of Uzbekistan is an endemic region with high degree of iodine deficiency. The aim of our study were investigate impact of COVID19 on thyroid function in people living in iodine defi...

Introduction: Hyperglycemia is often elevated in patients with acute myocardial infarction (AMI) and is a prognostic indicator. According to a number of researchers, the risk differs between women and men. The purpose of our study was to study the effect of hyperglycemia on clinical and biochemical parameters in men and women with AMI. Materials and methods: The study was conducted on 92 patients admitted to the intensive care unit of the cardiology cent...

Introduction: In some cases pubertal growth and sexual maturation and relating normal physiology can be disturbed and retarded by chronic disease as like Diabetes Mellitus (DM). According to International Diabetes Federation Atlas in 2013 approximately 5, 00, 000 known cases of children with T1DM (0–14 years) worldwide, where 50-60% of cases are diagnosed before the age of 15. Insulin deficiency in T1DM presented with age in childhood and visible peaks at the time of pube...

Introduction: Diabetes mellitus (DM) has emerged as a significant global health concern, contributing to increased mortality and complications, thereby adversely affecting overall quality of life. The incrising incidence of DM, particularly type-2 DM (T2DM), correlates with rising rates of various cancers, suggesting a potential direct link between DM and cancer. Mounting evidence suggests DM as a potential contributor to the heightened incidence of endometrial cancer (EC) and...

Introduction: Malignant tumors of the thyroid gland are common in the field of endocrinology as an oncological disease. The diagnosis of thyroid cancer (TC) is based on sonographic and cytological methods. The widespread use of TI-RADS classification and the Bethesda System for Reporting Thyroid Cytopathology proposed by the American College of Radiology (ACR) and the U.S. National Cancer Institute (NCI) relatively significantly increases diagnostic accuracy. In this study dia...

Introduction: Diabetes Mellitus (DM) is one of the Global pandemics despite to new knowledges and methods of prevention and therapy intensively increased among children, adolescents and adults. Many studies shown the role of the gastrointestinal microbiocenosis in the development and clinical future of DM. Gut microbiota produce numerous bioactive molecules, which can act locally and secreted into bloodstream. The aim of our study were evaluation of gut microbiota in children ...

Introduction: Past years with increasing of duration of life, improving of treatment and increasing of life longevity and new knowledges about Diabetes Mellitus pathogenesis and treatment rise interest to reproduction in these women, especially with type 1 DM. Well known, that late puberty, abnormal menstrual cycle, pregnancy and childbirth pathology, infertility. The aim of our study was investigate the functional state of reproductive system in woman with DM1.<p class="a...

Introduction: Renin angiotensin system play a crucial role in the development of Diabetes Mellitus and its complications. According many studies, plasma renin level increased at the DM. However, mechanisms of its elevation is not clear yet. The aim of our study was compare plasma renin level in DM1 and DM2 patients and its relationship with glycemic control.Material and Methods: In 44 people with DM1 and 85 with DM2 whose admitted into Hospital of the Re...

Introduction: The purpose of this work was monitor the frequency of determination and compare the levels of parathyroid hormone in blood plasma in people on programmed hemodialysis.Material and methods: Data from medical records of 465 patients on programmed hemodialysis who were admitted to the Republican Centre of Nephrology and Kidney Transplantation were analyzed. Patients according to reason of end stage of renal failure were divided into 3 groups d...

Introduction: Metabolic disturbances at the Diabetes Mellitus (DM) leads to structural and functional abnormalities of the cell plasma membrane due to changes in the lipid content and composition, especially phospholipids. Plasmalogens are unique group of phospholipids with alcohol and ether bounds, presented in a few papers. We hypothesis their involvement into pathogenesis of DM.Material and methods: We studied the content of Plasmalogens in blood plas...